Biological Relationships of Diplococcus Intracellularis and Gonococcus

Standardization of the Antimeningitis Serum

The high variability in infectivity of Diplococcus intracellularis makes it impracticable to standardize the antimeningitis serum on the basis of the virulence of the diplococcus. The irregularity of reaction of small animals to the poison or endotoxin of Diplococcus intracellularis makes it impracticable to standardize the antimeningitis serum on the basis of endotoxic value. The want of unifo...

Mucosal Immunity and Evasion Strategies of Neisseria gonorrhoeae

Neisseria gonorrhoeae, the gonococcus, is a gram-negative diplococcus which causes the sexually transmitted disease gonorrhea (Figure 1). The contagious nature of gonococcal infection remains a major global health problem and represents 88 million new cases every year (WHO, 2011). N. gonorrhoeae is transmitted by human to human contact and is highly adapted to the genital tract, surviving poorl...

Occurrence of neisseria other than the gonococcus in the genital tract.

Cultural methods are now widely used for the diagnosis of gonorrhoea, and a positive culture offers the only incontrovertible proof of the diagnosis. The bacteriological criteria for the identification of the gonococcus are clearly defined, but in routine work they are not always stringently applied. An organism with an oxydase positive colony which microscopical examination shows to be a Gram-...

Notes on Two Cases of Cerebrospinal Meningitis Due to the Diplococcus Intracellularis, Treated with Intrathecal Injections of Anti-Meningococcic Serum (Mulford), in a Field Ambulance in Mesopotamia

a Comparative Study of the Diplococci Occurring in Epidemic Cerebro-spinal Meningitis and Posterior Basic Meningitis

The study carried out and recorded in this paper did not lead to the finding of any reliable criteria of difference between strains of Diplococcus intracellularis obtained from typical cases of epidemic meningitis and several cultures obtained from cases of posterior basic meningitis. The successful experiments made with monkeys show that the diplococcus obtained from cases of posterior basic m...